I'm used to Thomasik Infeld flatwounds, and these are an interesting alternative
Pros: nice smooth strings, a different tonality, should last ages
Cons: you probably have to do alterations to your nut and setup for these, as few guitars are set for strings this thick
Overall: I will probably stick with TI flats for the time being, not because I don't like these, but due the extra work of getting the guitar nut cut for such thick strings. But do give them a try!