I use SML21 (line signal combiner) to connect 2 mixers to one amplifier, so I don't have to change settings, or rewire the main mixer. I haven't noticed any change that this device makes to the sound in live setting. SML21 looks and feels solid built, but as I haven't used it long enough, I cannot comment on reliability.A very useful tool, in my opinion.
EDIT: there's some slight drop in level when using this combiner, probably because it is a passive device