I use these when I'm rebuilding pedalboards, trying out pedals, finding out the best order etc., so you can imagine they get pulled, bent and twisted a lot.
I mainly do that to avoid messing too much with fencier, more expesince cables. When I get my final setup and pedal order, I change these patch cables with more professional ones.
I played a few gigs with them, when I didn't manage to change them with fancier ones before the gig, and they worked perfectly OK.
I never had a problem with excessive sound loss, at least not noticably more than with other patch cables.
Having a straight jack they work best with pedals that have top mounted jack sockets. I'd prefere if they had an angular jack on one side, instead od two straight jacks, so that they'd be easier to combine with effects with side mounted jacks.
Not the best audiophile cables, but they do the job and are great value for the money.