I used d'Aaddario Chromes for years, but recently switched to TI JS113's. I prefer the feel and the slightly lower tension. I've used them on full-body jazz guitars and semi's. They will only suit people who like heavy flatwounds (my brother calls them 'unplayable railway lines') but if you're into that sound, I've not found better (although I've not tried GHS). Note I also use a heavy pick (2mm). I'm not sure they'd sound too good with a light or even a medium attack. They're a tad more expensive than d'Addario's, but well worth it imho. I've had one set on a semi for 10 months, and they're still pretty bright, with no intonation or tuning problems, so I'd give them high marks for longevity and cost-effectiveness. If you're a heavy string-bender or hammer & pull stylist, they're going to be tough to play cleanly. But if you're into a rich mellow kind of sound, without the 'twang & buzz' of round-wounds, you're probably on flats already. These things are very personal, so don't take my word for it (or anyone else's). I'd say give them a try & see what you think.