We bought these as the main sound output from the A/V system of our Baptist chapel. It's a medium sized room, quite resonant, and with a high ceiling.
These speakers are perfect for us. They are quite unobtrusive (mounted on the side walls with L brackets) and give a very clear and natural sound. They cope very well with speech and with our small music group consisting of piano, guitar, and a singer, as well as a range of pre-recorded material.
You just have to be realistic about the amount of bass you can expect from speakers of this size. For our use it isn't a problem. With higher volume levels and a larger band, and especially if the band included a bass, you might feel something is missing. Nothing that the addition of a separate sub-woofer couldn't solve though.